How to Future-Proof Your Brain and Think Smarter in the 21st Century
With the world around us evolving at an ever-greater pace, especially with the rapid explosion of AI, you might fantasize about upgrading your brain to make sense of it all. While our grey matter hasn’t physically changed much since the Stone Age, neuroscientists believe we possess an incredible capacity for mental flexibility.
According to neuroscientist Hannah Critchlow, author of The 21st Century Brain, understanding neuroscience can unleash the cognitive potential we all have to navigate the ambiguity and rapid changes of the modern era.
1. Cultivate Emotional Intelligence
Emotional intelligence and empathy are often dismissed as “soft skills,” but they are crucial for survival and innovation in the 21st century. While genetics play a small role, these skills are highly trainable. It starts with self-compassion: taking the time to ask yourself, “Why am I feeling this emotion?” By being compassionate to yourself, the effects naturally ripple out to others.
2. Nurture Your Gut-Brain Connection
Did you know your altruism might come from your gut? A fascinating study from Insead in France showed that healthy volunteers taking pre- and probiotics for just seven weeks developed a more varied gut microbiome—and became significantly more altruistic. The millions of nerves in our gut communicate directly with the decision-making parts of our brain via the vagus nerve, meaning our physical gut health directly shapes our social interactions.
3. Optimize Your Bioenergetics
Our brains use vast amounts of energy to perform mental gymnastics. This relies heavily on mitochondria—the tiny powerhouses inside our cells. Anything we do to help our mitochondria create clean energy, like exercising and keeping physically fit, will protect our neural connections and help our brains cope with modern challenges.

Further Reading: Upgrade Your Mind
Ready to dive deeper into the neuroscience of the 21st century? Add these highly recommended books to your reading list:
- The 21st Century Brain by Hannah Critchlow: The inspiration for this article, detailing how to flourish in the age of AI.
- The Brain That Changes Itself by Norman Doidge: A classic exploration of neuroplasticity and how the brain can rewire itself.
- The Mind-Gut Connection by Emeran Mayer: Explores the hidden conversation within our bodies that impacts our mood and decisions.
- Thinking, Fast and Slow by Daniel Kahneman: The ultimate guide to understanding how our minds make decisions and how to avoid cognitive biases.
Source: BBC Future – A neuroscientist’s guide to future-proofing your brain
Co-Founder, OmOrenda.space & Tech Executive
Bijay Niraula is a Silicon Valley-based technology entrepreneur and ecosystem builder operating at the cutting edge of AI, blockchain, and human optimization. As the co-founder of OmOrenda.space—the Basecamp for Human Flourishing—Bijay leads a dual-shored AI and blockchain company with a vibrant workforce spanning both the San Francisco Bay Area and Nepal. His core mission is to bridge advanced U.S. technology with deep-rooted global traditions, using modern innovation to bring ancient wisdom to light.
Under his leadership, OmOrenda bridges the gap between Eastern mindfulness practices and Western empirical science. Collaborating alongside US-trained neuroscientists and Stanford longevity faculty, Bijay drives pioneering research that includes collecting EEG brainwave data from advanced meditators and mapping the physiological, vibrational effects of traditional Nepalese singing bowls.
Deeply committed to cross-border knowledge transfer, Bijay actively organizes and participates in high-impact AI and Wellness intersection hackathons in both the Bay Area and Nepal. By leveraging his extensive Silicon Valley network, his ultimate vision is to champion the success of Nepal’s national Wellness 2027 initiative—exporting world-class U.S. technology, capital, and research to Nepal while showcasing the country’s rich wellness heritage to the global stage.
Connect on LinkedIn: https://www.linkedin.com/in/web3-silicon-valley/

